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The Body Scientific

Treating opioid abuse: costly research is well worth it

We like every catastrophe to have a single cause because a villain, especially one that had been identified, is a satisfying thing. In the case of opioid use disorder, one villain is Purdue Pharma, makers of OxyContin, a powerful pain reliever and euphoric that the company claimed was not addictive. It is addictive, but so are   enormous profits. Purdue is getting its slow-drip punishment, in the form of massive lawsuits, and it faces insolvency.

What biology tells us about addiction

Second of a series on opioids

 

What biology tells us about our bodies and addiction

Second of a series on opioids

 

First, there was opium

The first in a series on opioid addiction

 

How do opioids relieve pain, cause euphoria and lead to an addiction that refuses to take “no” for an answer? How is it that in 2017, 72,000 Americans died of opioid drug overdose? What is the chemistry behind this catastrophe? Is there any hope of controlling it?

What biology tells us about addiction

Second of a series on opioids

 

First, there was opium

The first in a series on opioid addiction

 

How do opioids relieve pain, cause euphoria and lead to an addiction that refuses to take “no” for an answer? How is it that in 2017, 72,000 Americans died of opioid drug overdose? What is the chemistry behind this catastrophe? Is there any hope of controlling it?

Does Prevagen help in reducing memory loss?

You may have seen the ad for Prevagen during morning news shows or between innings of a Red Sox game: a video of a pulsating jellyfish, whose nervous system glows blue. The substance that provides the blue glow is protein called apoaequorin and it is very well studied. 

The case of Spinal Muscular Atrophy: Deadly inherited diseases start to yield

Part 1

A few years ago, a friend asked me if I could take over a basic science lecture he was scheduled to give to 220 first-year medical and dental students at Columbia’s Vagelos College of Physicians and Surgeons. He had to go to a wedding or take a kid to college or some such. He handed me his PowerPoint presentation, grinned and said, “Good luck.” I had two weeks to work on it.